Applications


SEDERE has generated a large number of application notes that describe the very extensive use of the SEDEX Low-Temperature Evaporative Light-Scattering Detection in LC and SFC. Although this is not an exhaustive list, it provides several examples showing how the detector is used to solve a broad range of analytical problems.

For more complete and recent information on ELSD technology and applications, you can also refer to our up-to-date SEDERE ELSD Bibliography.

Key:

Technique: CCC=Counter Current Chromatography, GPC=Gel Permeation Chromatography, HPLC=High Performance Liquid Chromatography, SFC=Supercritical Fluid Chromatography.

Compound Chemical Class Technique Application Number
Acesulfam – K Sweetener HPLC 144
Acetylenecarboxilic Acid Organic Acid HPLC 91
Aconitic Acid Organic Acid HPLC 102
Alanine Amino Acid HPLC 114 – 123
Aliphatic Alcohols Fatty Alcohol SFC 34
Alkyl
Glucosinolates
Thioglucoside HPLC 73
Alkylglycosides Detergent HPLC 25
Alkylglycosides Detergent SFC 27
Androsterone Steroid HPLC 28
Arachidonic Acid Fatty Acid HPLC 31
Arginine Amino Acid HPLC 90
Asparagine Amino Acid HPLC 113
Aspartame Sweetener HPLC 144
Aspartic Acid Amino Acid HPLC 114
Bisulfan Sulfonic Ester HPLC 82
Bromide Anion HPLC 145
Caffeine Alkaloid SFC 12
Calcium Cation HPLC 106
Beta Carotene Terpenoid HPLC 100
Cerebroside Phospholipid HPLC 5
Cetylbetaine Detergent HPLC 145
Cetylpyridinium
Chloride
Aromatic HPLC 14
Cetrimide Antiseptic HPLC 103
Chloramphenicol Antibiotic SFC 12
Chloride Anion HPLC 106
Cholesterol Steroid HPLC 41
Citric Acid Organic Acid HPLC 38
Citrulline Amino Acid HPLC 125
Corticosterone Steroid HPLC 92
Cyclamate Sweetener HPLC 144
Cyclodextrins Oligosaccharide HPLC 79
Cysteine Amino Acid HPLC 114 – 115
Decanoic Acid Fatty Acid HPLC 32
Decyl Beta – D
Glucopyranoside
Detergent HPLC 25
Decyl Beta – D
Maltoside
Detergent HPLC 25
Decyl Sulfate Detergent HPLC 145
Dehydro – epi –
Andosterone
Steroid HPLC 28
Deoxyribose Carbohydrate HPLC 74
Deoxyribose Carbohydrate SFC 49
Dextrans Carbohydrate HPLC 11
Dextrose (D –
Glucose)
Carbohydrate HPLC 144
Dimyristolphosphatidyl
Choline
Phospholipid HPLC 95
Diolein Lipid HPLC 99
Dimyristolphosphatidyl
Glycol
Phospholipid HPLC 95
Docosanoic Acid Fatty Acid SFC 3
Docosanol Fatty Alcohol SFC 34
Dodecylcyclophosphoethanolamine Phospholipid HPLC 83
Dodecylcyclophophocholine Phospholipid HPLC 83
Dodecylsulfate Detergent HPLC 145
Dehydrophenylalanine Amino Acid HPLC 126
Eicosanol Fatty Alcohol SFC 34
Ergocalciferol Vitamin HPLC 101
Estradiol Steroid HPLC 29
Estrone Steroid HPLC 29
Ethiocolanone Steroid HPLC 28
Ethylene Glycol Glycol HPLC 141
Fatty Acids Fatty Acid CCC 48
Fluorodopa Amino Acid HPLC 133
Fructose Carbohydrate HPLC 1 – 8 – 11 – 44 – 74 – 75 – 77 – 143
Fructose Carbohydrate SFC 10 – 49 – 50
Fructose (Beet) Carbohydrate HPLC 45
Fructose (Chervil
Root)
Carbohydrate HPLC 47
Fructose
(Tabacco)
Carbohydrate HPLC 46
Fumaric Acid Organic Acid HPLC 38
Galactose Carbohydrate HPLC 59
76
Ginseng Saponins Terpenoid HPLC 60
Glucose Carbohydrate HPLC 1
Glucose Carbohydrate SFC 10 – 49 – 50
Glucose
(Beet)
Carbohydrate HPLC 45
Glucose
(Chervil Root)
Carbohydrate HPLC 47
Glucose
(Tabacco)
Carbohydrate HPLC 46
Glutamic Acid Amino Acid HPLC 115
Glutamine Amino Acid HPLC 114
Hexacameg HPLC 84
Hexacosanol Fatty Alcohol SFC 34
Hexadecanol Fatty Alcohol SFC 34
Hexyl Beta – D
Glucopyranoside
Detergent HPLC 25
Histidine Amino Acid HPLC 113
Hormonal Steroids Steroid HPLC 28
Inositol Phophate Polyol HPLC 80
Isoleucine Amino Acid HPLC 113
Lactose Carbohydrate HPLC 11
Lactulose Carbohydrate HPLC 105
Lauric Acid Fatty Acid HPLC 40
Lauric Acid Fatty Acid SFC 3
Lauryldimethylbenzyl
Ammonium Chloride
Detergent HPLC 145
Laurylpyridium
Chloride
Detergent HPLC 145
Leucine Amino Acid HPLC 90
Linoleic Acid Fatty Acid HPLC 81
97
Lipid Placebo Lipid HPLC 95
Lubrol Detergent HPLC 61
Lysine Amino Acid HPLC 90
Lysophosphatidyl Choline Phospholipid HPLC 5
Lysophosphatidyl Ethanolamine Phospholipid HPLC 98
Magnesium Cation HPLC 106
Malic Acid Organic Acid HPLC 38
Maltodextrins Polysaccaride HPLC 35
Mannitol Polyol HPLC 44
Mannitol Polyol SFC 50
Mannose Carbohydrate HPLC 44
Mannose Carbohydrate SFC 49
Melibiose Carbohydrate HPLC 77
Meso – Erythritol Polyol SFC 49
Methyl a,b -D
Glucopyranoside
Detergent HPLC 25
Methionine Amino Acid HPLC 113
M-Inositol Polyol HPLC 76
Monoolein Lipid HPLC 99
Morphine Alkaloid SFC 33
Myristic Acid Fatty Acid SFC 3
Narcotine Alkaloid SFC 33
Nitrate Anion HPLC 106
Norleucine Amino Acid HPLC 131
Norvaline Amino Acid HPLC 132
Octadecanol Fatty Alcohol SFC 34
Octyl Beta – D
Galactopyranoside
Detergent HPLC 25
Octyl Beta – D
Galactopyranoside
Detergent SFC 27
Octyl Beta – D
Glucopyranoside
Detergent HPLC 25
Octyl Beta – D
Glucopyranoside
Detergent SFC 27
Octyl Beta – D
Xylopyranoside
Detergent HPLC 25
Octyl Beta – D
Xylopyranoside
Detergent SFC 27
Octyl Beta – Glucoside Detergent HPLC 61
Oleic Acid Fatty Acid HPLC 97
Opium Alkaloids Alkaloid SFC 33
Oxytocyn Acetate Peptide HPLC 117
Palmitic Acid Fatty Acid HPLC 97
Palmitic Acid Fatty Acid SFC 3
Parafilm Hydrocarbon HPLC 42
Parafilm Hydrocarbon SFC 43
Peptides Peptide HPLC 93
Phenobarbital Anticonvulsant SFC 12
Phenylalanine Amino Acid HPLC 113
Phenylbutazone NSAID SFC 12
Phosphatidic Acid Phospholipid HPLC 5
Phosphatidyl
Choline
Phospholipid HPLC 5
Phosphatidyl Ethanolamine Phospholipid HPLC 5
Phosphatidyl Glycerol Phospholipid HPLC 98
Phosphatidyl
Inositol
Phospholipid HPLC 5
Phosphatityl Serine Phospholipid HPLC 5
Pinitol Polyol HPLC 56
Polybutylene Glycol Polymer HPLC 86
Polyethoxylated
Alcohols
Polymer HPLC 87
Polyethoxylated
Alcohols
Polymer SFC 87
Polyethylene
Bimodal (High MV)
Polymer GPC 70
Polyethylene
Glycol PEG 10 Tridecyl Ether
Detergent HPLC 61
Polyethylene
Glycol PEG 1450
Polymertd> HPLC 54
Polyethylene
Glycol PEG 1450
Polymer SFC 88
Polyethylene
Glycol PEG 300
Polymer HPLC 21
Polyethylene
Glycol PEG 300, 400
Polymer SFC 51
Polyethylene
Glycol PEG 400
Polymer HPLC 23
Polyethylene
Glycol PEG 600
Polymer HPLC 24
Polyethylene (NBS
1475)
Polymer GPC 69
Polyoxyethylene
Alcohol C12 E7
Polymer HPLC 19
Polyoxyethylene
Alcohol C12 E9
Polymer HPLC 17
Polyoxyethylene
Alcohol C16 E7
Polymer HPLC 20
Polyoxyethylene
Alcohol C16 E10
Polymer HPLC 18
Polyoxyethylene
Alcohol C18 E10
Polymer HPLC 16
Polyoxyethylene
Alcohols
Polymer HPLC 89
Polysaccharides
(In Beer)
Carbohydrate HPLC 9
Polysorbate 20 Polymer HPLC 15
Polystyrene (Dow
1683)
Polymer GPC 68
Polystyrene
Standards
Polymer GPC 62 – 63 – 64 – 65 – 66 – 67
Potassium Cation HPLC 106 – 107 – 111
Prednisolone Steroid SFC 12
Progesterone Steroid HPLC 28
Proline Amino Acid HPLC 113 – 114 – 134
Raffinose Carbohydrate HPLC 1 – 11 – 74 – 75 – 77
Raffinose Carbohydrate SFC 10
Raffinose (Beet) Carbohydrate HPLC 45
Rhamnose Carbohydrate HPLC 74
Saccharin Sweetener HPLC 144
Serine Amino Acid HPLC 114
Sodium Dodecyl
Sulfate
Detergent HPLC 61
Sodium Cation HPLC 106
Sorbitol Polyol HPLC 1
Sorbitol Polyol SFC 50
Soybean Oil
(Hydrolyzed)
Lipid HPLC 118
Sphingomyelin Phospholipid HPLC 5
Stachyose Carbohydrate HPLC 75
Stearic Acid Triglycerides HPLC 97
Stearic Acid Triglycerides SFC 3
Stigmasterol Steroid HPLC 97
Succinic Acid Organic Acidtd> HPLC 38
Sucralose Sweetener HPLC 143
Sucrose
(Saccharose)
Carbohydrate HPLC 1 – 8 – 11  – 74 – 75 – 77 – 143
Sucrose
(Saccharose)
Carbohydrate SFC 10
Sucrose
(Beet)
Carbohydrate HPLC 45
Sucrose
(Chevil Root)
Carbohydrate HPLC 47
Sucrose
(Tabacco)
Carbohydrate HPLC 46
Sugars
(Mono-Oligosaccharides)
Carbohydrate HPLC 76
Sugars
(Douglas Fir Needles)
Carbohydrate HPLC 56
Sugars
(Milk)
Carbohydrate HPLC 59
Sugars
(Tabacco)
Carbohydrate HPLC 8
Sulfate Anion HPLC 106
Surfactants Detergent HPLC 145
Tartaric Acid Organic Acid HPLC 38
Tergitol Detergent HPLC 61
Tetracosanoic Acid Fatty Acid SFC 3
Tetradecanol Fatty Alcohol SFC 34
Threonine Amino Acid HPLC 114
Alpha – Tocopherol Vitamin HPLC 97
Beta – Tocopherol Vitamin HPLC 97
Delta – Tocopherol Vitamin HPLC 97
Gamma – Tocopherol Vitamin HPLC 97
Triacontanol Fatty Alcohol SFC 34
Trilaurin Lipid SFC 4
Trimyristin Lipid SFC 4
Triolein Lipid HPLC 99
Tripalmitin Lipid SFC 4
Tristearin Lipid SFC 4
Triton X 100 Detergent HPLC 22
Tryptophan Amino Acid HPLC 113
Tyrosine Amino Acid HPLC 113
Urea Carbamide HPLC 78
Valine Amino Acid HPLC 113
Vitamin A Vitamin HPLC 100
Vitamin D2 Vitamin HPLC 101
Vitamin E Vitamin HPLC 100
Vitamin E1 Vitamin HPLC 101
Vitamin K Vitamin HPLC 100
Vitamin K1 Vitamin HPLC 101
Xylene Sulfonate Detergent HPLC 145
Xylitol Polyol SFC 49
Xylose Carbohydrate HPLC 76
Zwittergent 3 14 Detergent HPLC 61

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